glp 1 small molecule A potent novel GLP-1R agonist identified by rational design and CADD A novel approach to exploit

Further investigation showed that CPs first reduce the level of skin oxidation, inhibit the expression of the key transcription factor AP-1 (c-Jun and c-Fos), then activate the TGF-/Smad signaling pathway to promote collagen synthesis, inhibit the expression of MMP-1/3 to inhibit collagen degradation, and inhibit skin inflammation to alleviate skin aging in mice

Choose a low concentration (e.g., 0.0025% if using a prescription form like Retin-A or a gentle over-the-counter retinol) and apply retinol to clean, dry skin 2 to 3 times a week in the evenings

I totally disagree and a lot of other professional experts disagree as well

References Skoracka K, Eder P, ykowska-Szuber L, Dobrowolska A, Krela-Kamierczak I (2020) Diet and nutritional factors in male (In)fertilityunderestimated factors