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A meta-regression analysis was conducted to examine the relationship between bupropion and the absolute mean differences in body weight, BMI, and waist circumference, taking into account the dosage and duration of the intervention
Amplifies beta-cell insulin secretion through pathways distinct from GLP-1R, modulates adipose tissue lipid handling, and appears to reduce the GI adverse-event burden associated with isolated GLP-1R agonism
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