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At MC4R, expressed in the paraventricular nucleus and other CNS regions, MT-2 activates pathways involved in sexual arousal and erectile function researchers observed that MC4R signaling stimulates oxytocinergic neurons that project to spinal centers controlling erectile tissue
Rather than activating only GLP-1 receptors, it is a dual agonist that also targets GIP (glucose-dependent insulinotropic polypeptide) receptors
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