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Our study implicates that targeting the estrogen-dependent system x c , specifically SLC7A11 and SLC3A2, with IKE through induction of ferroptosis in ER+ breast cancer cells, should offer a new therapeutic option for patients with ER+ breast cancer, particularly those with endocrine resistance
However, GPX4 proved to be a more attractive candidate for silencing lipooxygenases and influencing cytokine signalling (45)
THE MATERIALS REFERENCED HEREIN ARE EXCLUSIVELY INTENDED FOR LABORATORY AND RESEARCH USE
hirsutum, O
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