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The covariates of sex, age, race, ethnicity, and renal function did not have relevant effects on the predicted exposure

doi: 10.4330/wjc.v12.i4.110 16 DegruttolaAKLowDMizoguchiAMizoguchiE

Tropifexor is another very potent non-bile acid agonist of FXR, which has been shown to be very effective in NASH in animal models and it is under evaluation [40, 41]

Some patients find that foods they previously enjoyed become less appealing or harder to tolerate, particularly in the early weeks of treatment or following dose escalations

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