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Cancer-associated fibroblasts modify the response of prostate cancer cells to androgen and anti-androgens in three-dimensional spheroid culture
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SpaMTPs metabolite annotation performance We compared the performance of SpaMTP and METASPACE using a publicly available benchmarking dataset containing seven spiked-in metabolites at defined spatial locations 20
In preclinical models its reported effects concentrate at or near the site of administration, where it appears to promote new vessel formation, support fibroblast activity and stabilise the local healing environment
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