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Knockdown of glutamate-cysteine ligase by small hairpin RNA reveals that both catalytic and modulatory subunits are essential for the survival of primary neurons
Protein amyloids build up in a variety of places, causing degenerative diseases
Multi-omics pathway mapping (Figure 7A) revealed interconnections among glutathione metabolism, ferroptosis, and neuroactive ligand-receptor interaction pathways, showed strong association with mitochondrial function and neuronal damage
Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth
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