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It is not recommended to take tetracycline and vitamin B12 simultaneously, and the reason is that tetracycline will interfere with the effectiveness and absorption of vitamin B12

Seek urgent same-day assessment or call 999 for emergency care if experiencing: Severe chest pain Severe shortness of breath Fainting or collapse Acute or rapidly worsening neurological deficits (such as new limb weakness, sudden gait disturbance, or bladder/bowel dysfunction) Persistent or worsening anaemia symptoms despite treatmentincluding breathlessness, chest discomfort, palpitations, or extreme fatigueshould trigger medical review

Cell Metabolism, 35 (1), 1235

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