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Previous studies identified that mutation of Y211 to phenylalanine resulted in reduced carnitine transport whereas the transport of the cationic probe compound tetraethylammonium was unaffected 16 , indicating that Y211, through its hydroxyl moiety, plays a role in recognising the carboxyl of carnitine

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Survodutide (BI 456906), developed by Boehringer Ingelheim and Zealand Pharma, is a once-weekly injectable GLP-1/glucagon dual receptor agonist

GLP-1 medications may be considered for individuals looking for a longer-term approach to weight management, particularly when combined with lifestyle changes and ongoing medical supervision