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In patients with progressive myoclonus epilepsy, a GSTT1 -null genotype has been associated with increased risk of developing the disease where it might contribute to enhanced susceptibility to oxidative stress 60
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Unfortunately, the Atherosclerosis Risk in Communities negative prospective study did not provide detailed information about a potential selection bias caused by vitamin supplement use (Folsom et al, 1998
Extending the incubation to 72 hours exacerbated these trends, and even GSH levels fell by 33%, and GSSG increased by 81% (Supplementary Figure 1g-l)
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