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Weight loss outcomes vary by agent and dose: high-dose semaglutide (2.4mg/Wegovy) has shown mean weight reductions of approximately 15% in the STEP clinical trials, while liraglutide (3mg/Saxenda) typically achieves 5-8% weight loss
Amphetamine craze: Desoxyn, Pondimin, and Redux showed promise but were pulled due to safety concerns
Retatrutide does not replace the foundations of diet and exercise
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