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By day 7, bacterial counts may exceed 10^3 CFU/mL, enough to cause injection site infection: redness, swelling, warmth, and potential abscess formation
Improving specificity, destroying the ability to transport to tumors, maintaining low toxicity, and stabilizing serum are key challenges when employing antimicrobial peptides to treat breast cancer
Importantly, non-perfect repair of DSBs or SSBs, such as non-homologous end joining (NHEJ) can produce DNA mutations that may ultimately lead to cellular death by apoptosis, although they may also contribute to cell survival (Hakem, 2008
These pathways are mediated through the secondary rise of Insulin-like Growth Factor 1 (IGF-1), which acts as a primary anabolic messenger in musculoskeletal tissues
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