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An observational study of obese T2D patients with concurrent MASLD (metabolic dysfunction-associated steatotic liver disease) showed that 12 weeks of liraglutide significantly increased gut bacterial diversity and shifted the community toward a profile more like healthy individuals ( Bacteroidota and Proteobacteria (class Bacilli also increased), whereas an active comparator (metformin) enriched different taxa ( Fusobacteria and Actinobacteria ) and had a larger effect on network connectivity of the microbiota

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Furthermore, even if tiny amounts reach the infant through breast milk, tirzepatide is a peptide