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This results in huge disparities in the cost of new and old glucose-lowering medications in some countries, limiting access to the full range of diabetes therapies in large segments of the population and creating a two-tiered system of treatment

Research shows that patients with certain genetic variants in the GLP1R gene (such as rs6923761) may require different dosing strategies to achieve the same weight loss outcome

This recent study builds on previous research that was conducted in mice

Given these uncertainties, the current consensus among healthcare providers leans towards discontinuing semaglutide in women planning to conceive and those who become pregnant