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proposed that a the phospholipid/Ca++ dependent brain pkc participated in the expression of neuroplasticity and demonstrated this effect using the phorbol acetate TPA to enhance the action of pkc to maintain LTP in rat hipoccampal neurons (Routtenberg et al., 1986), in effect, producing a a long-lasting potentiation of synaptic activation (Colley et al., 1989)

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glucose tolerance test (IPGTT) or plasma glucose during ad libitum (AL) feeding (Extended Data Fig

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