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Physiological melanin hyperpigmentation is the result of increased melanin biosynthesis by melanocytes in the basal cell layer of the oral epithelium, but pathological melanin pigmentation may be the result of increased number of normal melanocytes or atypical melanocytes, of increased melanogenic activity of normal or atypical melanocytes, or of both

These cases collectively suggest a potential link between semaglutide use and the development or exacerbation of depressive symptoms, warranting closer monitoring in clinical practice

This means faster recovery from environmental stressors and a quicker turnover of old cells for new, healthy ones