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Thiazolidinedione use is associated with reduced risk of Parkinsons disease in patients with diabetes: a meta-analysis of real-world evidence
From its initial use in the treatment of type 2 diabetes to its expansion to 12 indications such as obesity, cardiovascular disease, chronic kidney disease, and metabolic dysfunction related fatty liver disease (MASLD), the annual sales of GLP-1 drugs exceeded 100 billion dollars, and its research and development funding reached a historical peak of 21.72 million dollars in 2025
Retatrutide dosage is generally increased every 4 weeks
Garcia-Navas et al., 2012)
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