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Researchers at Johns Hopkins Medicine have also documented a striking degree of neuroinflammation in these patients

J Neurochem 104:113123 Czeredys M, Mysiorek C, Kulikova N, Samluk L, Berezowski V, Cecchelli R, Nalecz KA (2008) A polarized localization of amino acid/carnitine transporter B(0,+) (ATB(0,+)) in the bloodbrain barrier

This has led to suggestions that excessive folic acid supplementation could, under certain circumstances, induce a functional folate deficiency

There is a sharp line between what controlled human studies of the individual agents measured and the specific dose numbers that circulate in research communities for the blend