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Author information Authors and Affiliations The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China Honglei Ma, Xiaoxi Wang, Lihua Zhao, Yi Jiang & H
Mutations in mitochondrial DNA (mtDNA), commonly detected across cancers such as renal oncocytoma, gastric adenocarcinoma, renal cell carcinoma, bladder cancer, ovarian cancer, thyroid cancer, and pancreatic cancer, 208,209,210,211,212,213,214,215 can disrupt OXPHOS, enhance ROS production, and promote tumorigenesis
[47] See Law.com, supra note 41
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