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Essentially, this design emulated a randomised controlled trial, in which participants on a background therapy with one of the drug classes of interest (GLP-1 receptor agonists or SGLT-2 inhibitors) are randomised to either continue the background drug or add on the other drug of interest (SGLT-2 inhibitor or GLP-1 receptor agonist, respectively)
IUBMB Life 68(2):97105 Khrle J (2015) Selenium and the thyroid
Who should and shouldnt try microdosing
10.1021/acs.accounts.5b00226 100 MittalM.SiddiquiM
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