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Less commonly, however, it may also cause severe nausea and vomiting , arthralgia , restless leg syndrome , skin color changes , and (in contradiction to the theory weve discussed) transient blood pressure increases .21 The likelihood and severity of these side effects may be dose- and duration-dependent: the stronger your dose and the longer you use the drug, the higher your risk of experiencing serious adverse events

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It has been shown that cells of the osteoblastic lineage generate 40-80% of their energy demands through fatty acid oxidation [153]