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IgG3 and IgG2 are notably transcytosed less efficiently than IgG1 and IgG4 [84], likely because of a missing glycine in the lower hinge of IgG2 [338] and an arginine instead of a histidine in amino acid position 435 in IgG3 [339, 340]
(Remember, a state of oxidative imbalance makes a person more susceptible to numerous diseases.) Therefore, having an ample supply of glutathione in the body is critical for maintaining health
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