fsp1 is a glutathione-independent ferroptosis suppressor

fsp1 is a glutathione-independent ferroptosis suppressor Protein 1 Inhibition Promotes Tumor Ferroptosis and Anti-tumor Immune Responses in Liver Cancer Structure and Function of FSP1

Name: fsp1 is a glutathione-independent ferroptosis suppressor Protein 1 Inhibition Promotes Tumor Ferroptosis and Anti-tumor Immune Responses in Liver Cancer Structure and Function of FSP1
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[1] Aspartyl residues in peptides are known to be susceptible to isomerization, and DSIP contains both an Asp residue and adjacent Gly the sequence context most associated with that rearrangement

J.HotalingJ

Among such species the radical forms are removed via non-enzymatic reduction with GSH, whereas the elimination of hydroperoxides requires enzymatic catalysis by GPX and catalase