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Christopher McGowan, M.D., a gastroenterologist specializing in obesity medicine and endobariatrics, explains that in addition to its effects on blood glucose and diabetes, GLP-1 also impacts weight via two key mechanisms: It affects the hunger centers in the brain (specifically, in the hypothalamus), reducing hunger, appetite and cravings

In a 2015 trial, oral tofacitinib was superior to placebo and as safe and effective as etanercept, one of the most widely used injectable biologics, for the treatment of moderate-to-severe plaque psoriasis

2025;:CPB-EPUB-151051