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Semaglutide is a medication primarily used to treat Type 2 diabetes

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Microbiota-driven gutbrain signaling underlies antidepressant effects of a GLP-1 analog by Liang Bian, Yang Cai, Yuan Zhang, Ling Shen, Huijuan Wang, Feng Gao, Ningbo Cai, Wenbo Chen, Conghui You, Yurui Yang, Fang Wang, Yonggui Yuan, Bing Han, and Honghong Yao

There is no absolute contraindication to taking Wegovy and Wellbutrin together, though it should be noted that concurrent use represents an off-label prescribing decision that should follow careful clinical assessment and shared decision-making