When present, classic findings include: Unilateral leg swelling (edema, increased limb circumference) Pain or tenderness along the course of the deep vein, often exacerbated by walking or dorsiflexion (Homans sign low specificity, rarely documented) Erythema or skin warmth over the affected limb Skin discoloration cyanosis (phlegmasia cerulea dolens in massive DVT) or pallor/blanching (phlegmasia alba dolens) Dilated superficial veins (collateral vessel prominence) Pitting edema distal to obstruction Upper extremity DVT may present with arm swelling, cyanosis, heaviness, or Paget-Schroetter syndrome (effort thrombosis in athletes/manual workers following strenuous use)
Neuropsychiatr Dis Treat 19:125 Smith GS, Oeltzschner G, Gould NF et al (2021) Neurotransmitters and Neurometabolites in Late-Life Depression: A Preliminary Magnetic Resonance Spectroscopy Study at 7T
This means that not only is this treatment effective, it is also becoming more accessible to those looking to improve their health and wellbeing
Some patients notice improvements in recovery and reduced inflammation within weeks, while others experience more gradual results