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Dual agonists target both the GLP-1R and another specific receptor, such as GIP (glucose-dependent insulinotropic polypeptide) or IGF (insulin-like growth factor) receptors
Impairment of NO signaling is one of the pathways that contributes to CVD and linagliptin has potent nitric oxide enhancing effects on vascular function [34, 118, 119]
Clinical trials establishing tirzepatide's safety and efficacy account for normal pharmaceutical variation, including minor air pockets
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