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Unraveling the transcriptomic signatures of homologous recombination deficiency in ovarian cancers

One large observational study found higher risk for diabetes in younger adults with low IGF-1, but not in adults older than 65

NHR-49 phosphorylation by the casein kinase KIN-19 After identifying a putative phosphorylation site at serine 114 and confirming its significance in controlling the subcellular dynamics of NHR-49 through mutational analysis, we next aimed to define the kinase responsible for this post-translational modification

Because Epithalon activates telomerasethe enzyme that maintains telomeres in our DNAthere's theoretical concern that it could accelerate growth of pre-existing cancer cells or dormant mutations