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Even on GLP-1s, which help regulate insulin and blood sugar levels, your body will eventually adapt to the medication and your new, lower body weight
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Several are now underway including the REMODEL T1D trial (semaglutide and kidney disease in T1D) and the SURPASS-T1D phase 3 trials (tirzepatide in T1D) with results expected in the coming years
21,22,23,24,25,26,27 However, these systems have several drawbacks, such as nonspecific distribution, inefficient cytoplasmic delivery, and suboptimal organelle targeting
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