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The authors additionally acknowledge: (a) Christopher Jadelis (at UNC Chapel Hill) for his assistance on the experimental setup
In B10.RIII mice immunized with interphotoreceptor retinoid-binding protein 161-180 (IRBP161-180), gut microbiota composition was analyzed on day 7 (pre-onset), day 14 (peak onset), and day 21 (chronic phase)
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Research demonstrates improvements in sleep onset latency, total sleep duration, sleep efficiency, and subjective sleep quality ratings without next-day drowsiness, cognitive impairment, or tolerance development
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