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These agents include thiazolidinediones (PPAR- agonists), dipeptidyl peptidase-4 (DPP-4) inhibitors, sulfonylureas, sodium-glucose co-transporter 2 (SGLT2) inhibitors, -glucosidase inhibitors, and glucagon-like peptide-1 (GLP-1) receptor agonists
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Common side effects Most side effects involve the stomach, tend to be mild to moderate, and usually ease as your body adjusts: Nausea Diarrhea Vomiting Stomach pain, bloating, and constipation Indigestion, heartburn (GERD), and burping Headache, dizziness, and tiredness Reduced appetite and weight loss Low blood sugar, mainly when taken with a sulfonylurea or insulin Serious side effects Get medical help right away if you notice any of these: Who should not take semaglutide
Semaglutide also delays the emptying of the stomach, which helps reduce appetite and promote satiety
