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The Link Between GLP-1 Receptors and Brain Function GLP-1 receptors are not confined to peripheral tissuesthey are also widely distributed throughout the central nervous system , including regions involved in cognition, reward processing, and executive function

While no widespread anaphylactic reactions were reported in clinical trials, there has been an isolated case of a severe local hypersensitivity reaction characterized by intense redness, swelling, and urticaria (hives) at injection sites in a patient who developed anti-sermorelin antibodies

Read more here: Everyones talking about GLP-1s

Issues like pernicious anemia and some gut problems can also cause it