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The DAC version (Drug Affinity Complex) binds to albumin in the blood and stays active for roughly 68 days
Reported preclinical doses (for documentary purposes only) vary by route: intranasal (high bioavailability, direct BBB crossing via olfactory and trigeminal pathways), intraperitoneal, subcutaneous
Jaeger-Lansky A, Schmidthaler K, Kuessel L, Gstottner M, Waidhofer-Sollner P, Zlabinger GJ, Wenzl R, Eiwegger T
Put the needle in the same square inch repeatedly and the fat underneath responds the way any tissue does to repeated small trauma: it thickens, it gets lumpy, and the lump absorbs the next dose less predictably than fresh tissue would
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