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Graphical Abstract Keywords 1
The recently completed large-scale REWIND trial randomized 9901 patients with T2DM to either placebo or dulaglutide
They Reduce Insulin Resistance GLP-1s help your body use insulin more efficiently, lowering blood sugar and reducing fat storageparticularly around the midsection
People who experienced significant wearing-off on semaglutide often find the effect more noticeable after switching to tirzepatide, not because tirzepatide is less effective, but because its shorter half-life creates a wider gap between peak and trough levels
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