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These might include additive, synergistic, or antagonistic effects that cannot be reliably predicted without dedicated pharmacokinetic and pharmacodynamic studies
107 A randomized clinical trial with 60 participants compared 1,140 mg per day of licorice to standard hormone replacement therapy (HRT) with 0.312 mg conjugated estrogens plus 2.5 mg medroxyprogesterone per day, taken for 90 days, on menopausal hot flashes
Boutari, C
doi: 10.2147/CMAR.S277013 51 MorandiARisalitiMMontoriMBucciantiSBartoliniIMoraldiL
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