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Iron chaperones PCBP1 and PCBP2 mediate the metallation of the dinuclear iron enzyme deoxyhypusine hydroxylase
The point is that MOTS-c's safety profile is harder to predict from first principles, and the data needed to narrow that uncertainty do not yet exist
Biomaterials 160 , 124137 (2018)
TERT siRNA in the combination background formally tests whether the additive effect requires both telomerase and Nrf2 pathways simultaneously (predicted by the mechanistic model TERT siRNA should abolish the Epitalon contribution but not the GHK-Cu contribution in the combination)
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