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That single chemical addition converts a brief, pulsatile GHRH stimulus into week-long GH and IGF-1 elevation, with once-weekly dosing in human trials versus the multiple daily administrations the no-DAC core's minutes-scale half-life would demand
K.LuoJ.LauC
Tirzepatide, which adds the GIP receptor, raised that to around 21 percent
To confirm its safety and effectiveness in extending human life, however, further extensive clinical trials are needed
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