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Janik, M
Estudios in vivo en cobayas han examinado las implicaciones farmacocinticas de la reduccin de la unin a la IGFBP, documentando concentraciones plasmticas reducidas de IGF-I, IGF-II y protena de unin al IGF, junto con efectos de crecimiento selectivos por rgano tras la infusin de LR3-IGF-1 en comparacin con el IGF-I endgeno [2]
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This suggests that Ex-4 mediates its protective effects through a GLP-1-R-SIRT1-p53 signaling axis [41]
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