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As a GLP-1 receptor agonist, semaglutide mimics the action of the naturally occurring hormone GLP-1, which helps regulate appetite and food intake

Collectively, these observations highlight the markedly heterogeneous nature of AA and underscore that its clinical course cannot be reliably predicted based solely on initial presentation

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Retatrutide has shown common side effects similar to other GLP-1 receptor agonists, including: Nausea Vomiting Diarrohea Constipation Abdominal discomfort or bloating Some trial participants experienced a slight increase in resting heart rate, which has also been observed with other GLP-1 receptor agonists