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By treating metabolically active adipocytes and hepatocytes with 5-amino-1-methylquinolinium, researchers can precisely inhibit intracellular NNMT activity, monitor changes in the nicotinamide pathway and NAD+ levels, and analyze effects on energy metabolism
Zhuang T, Gu X, Zhou N, Ding L, Yang L, Zhou M
Molecular profiling: Assessment of VEGF receptor levels, FAKpaxillin phosphorylation, collagen I/III expression, and nitric oxide synthase activity to elucidate mechanistic pathways
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