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Oral semaglutide is made up of the same active ingredient as injectable GLP-1s, working to slow digestion, reduce appetite, regulate insulin sensitivity, and support weight loss
(Align these procedures with 21 CFR 211.22
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Here is some more commentary from alzforum on the liraglutide trial: According to the published trial protocol, clinical secondary outcome measures included change on the ADAS-Cog-Exec z scorewhich contains the ADAS-Cog and the executive function portion of the neuropsychological test batteryas well as the Clinical Dementia Rating Scale Sum of Boxes and the AD Cooperative StudyActivities of Daily Living (Femminella et al., 2019)
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