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A recent meta-analysis confirms its efficacy in reducing HbA1c and body weight, though its gastrointestinal adverse event risk necessitates careful patient monitoring ( Effective management of gastrointestinal adverse events associated with GLP-1 receptor agonists and multi-target agonists is critical to optimize their therapeutic application in type 2 diabetes management

We believe that significant efforts should be put into investigating in greater detail the pathways shared by eryptosis and erythronecroptosis, like caspase-8, ROS signaling, Fas/FasL signaling, to collect more evidence on the interplay between these erythrocyte-specific RCDs

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