increased heart rate tirzepatide with and Cardiovascular Outcomes: A Narrative Review of Mechanisms, Efficacy and Implications High heart rate during exercise

Disproportionate Visceral Fat Reduction Tirzepatide reduces visceral adipose tissue beyond what total weight loss data would predict a metabolically significant effect because VAT is the primary driver of insulin resistance, cardiometabolic risk, and the inflammatory burden of obesity

Baseline cardiovascular assessment should be performed before initiating tirzepatide therapy

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