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They are fundamentally different medications with different mechanisms, different outcomes, and different patient populations
Monitor blood glucose levels more frequently, check ketones if advised by your healthcare team, and consider temporarily adjusting other diabetes medications (particularly insulin, metformin or SGLT2 inhibitors) after seeking clinical advice if you're unable to eat or drink normally
EuroQol Group, Rotterdam, The Netherlands Beaudet A, Clegg J, Thuresson PO, Lloyd A, McEwan P (2014) Review of utility values for economic modeling in type 2 diabetes
These results make the Retatrutide vs Tirzepatide weight loss comparison one of the most compelling in recent metabolic pharmacology literature, though Phase 3 confirmation remains pending
