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such effects of DPP-4 inhibition on autophagy signaling were completely abolished by GLP-1R antagonist exendin 9-39 coadministration ( DPP-4 and Extracellular Matrix Interaction: Relevance to Autophagy Suppression Other than GLP-1 induction, the pleiotropic effects of a DPP-4 inhibitor may be relevant to the mechanisms of autophagy induction by DPP-4 inhibition
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The oral form typically requires daily intake at higher doses to match injectable potency
Reported that hirudin might play a direct or indirect role in regulating cellular metabolism, oxidative stress, and other mechanisms in the treatment of DKD
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