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This resource is designed to help professional researchers design their studies while furthering their understanding of the mechanisms behind 5-amino-1MQ
While this effect appears to be related to the magnitude and rapidity of glucose lowering rather than a direct effect of the medication itself, patients with a history of diabetic retinopathy should undergo careful ophthalmologic evaluation before and during treatment, and the potential risks should be weighed against the expected benefits of improved glycemic control
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Most clinicians recommend a trial period of 48 weeks with dose adjustment before determining efficacy
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