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We did not pool mortality data in a meta-analysis because most deaths occurred in a single trial which recruited exclusively patients at increased cardiovascular risk (25 deaths with tirzepatide and 35 deaths with insulin glargine) [21]

Adjustments should be made under medical supervision to balance efficacy and safety

Further, researchers should always use aseptic techniques to ensure the purity and sterility of the mixture and refer to the label of the peptide for accurate information on reconstitution, handling, and storage

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