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Testing the effects of the GLP-1 receptor agonist Exenatide on cocaine self-administration and subjective responses in humans with cocaine use disorder
Overall, 157 people with MASH (diagnosed by biopsy) and moderate or severe fibrosis of the total 190 study participants were administered subcutaneous doses of Tirzepatide 5 mg, Tirzepatide 10 mg, or Tirzepatide 15 mg or a placebo every week
Notably, among all GLP-1 RAs, liraglutide stood out for its association with AP events related to acute pancreatitis
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