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Interestingly, DSIP doesn't bind directly to opioid receptors like morphine or endorphins
After blocking with 5% BSA, the sections were incubated with 1:200 anti-GLP-1 (ab23468, Abcam), followed by detection with secondary antibodies Alexa Fluor 488 conjugated goat antibody to mouse IgG (A-11029, ThermoFisher
These options can provide a consistent supply and allow for more flexible dosing under medical supervision, which is particularly helpful during national shortages of branded products
Patients considering compounded semaglutide should discuss the potential risks and benefits with their healthcare provider and verify the compounding pharmacy's credentials and quality standards
