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It has been speculated that the continued use of bethanechol may result from its use in patients who find the option of undergoing urinary catheterisation intimidating & choose to exhaust less invasive treatment options first, or in select patients where it seems to provide a marginal benefit (Gaitonde et al, 2019)
The here-proposed catalytic involvement of arGSTs in the biosynthesis would profit from such association with metabolons and is indirectly observed through the enzymes localization to membranes in planta 30
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